10 Best Pancreatic Enzymes For Dogs of 2026

Last updated on 04/02/2026
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Best Choice
1
9.7
Exceptional
Woofy Pancreatin Digestive Support | Pancreatic Digestive Enzymes | 10x Pancreatin | No Odor | Pancreatin for Dogs and Cats | Pancreatic Enzyme | Great for Pets with EPI | 250 Grams
Woofy

Woofy Pancreatin Digestive Support | Pancreatic Digestive Enzymes | 10x Pancreatin | No Odor | Pancreatin for Dogs and Cats | Pancreatic Enzyme | Great for Pets with EPI | 250 Grams

Why we love it
  • Odorless and safe to use.
  • Potent enzyme support for pets.
  • Tested for purity and potency.
Main Highlights
  • Powerful digestive support: Features 10× pancreatin with high levels of lipase, protease, and amylase to help break down fats, proteins, and carbohydrates for optimal digestion.
  • Without dust & odorless formula: Specially crafted to minimize dust and smell, making it easy and comfortable to mix into your pet’s food.
  • Ideal for pets with EPI & digestive issues: Supports dogs and cats suffering from exocrine pancreatic insufficiency or other conditions where natural enzyme production is limited.
  • Third-party tested for purity: Every batch is independently lab-tested to ensure quality, safety, and effectiveness you can trust.
  • For dogs & cats of all sizes: A versatile supplement that promotes nutrient absorption, energy, and overall wellness for pets of any age or breed.
9.7
Exceptional
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Best Value
2
9.5
Superb
Pan-tenex | 10x Digestive Enzymes for Dogs - 8.8 Ounces (250 Grams)
Pan-tenex

Pan-tenex | 10x Digestive Enzymes for Dogs - 8.8 Ounces (250 Grams)

Why we love it
  • Highly effective digestive support.
  • Optimal nutrient absorption guaranteed.
  • Cost-efficient, easy-to-use dosing.
Main Highlights
  • Highest Potency Available – 10x Porcine Pancreatic Enzyme Powder
  • Maximum Enzyme Levels To Support Digestion Of Fats, Proteins & Carbohydrates
  • Contains Lipase, Amylase & Protease Digestive Enzymes For Nutrient Absorption
  • Acetone-Free | Dust-Free | Low-Odor Formulation
  • Dosed Per Meal, Not Per Cup Of Food | Use Less & Save More
9.5
Superb
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3
9.3
Superb
PancreaMax 10x Pancreatic Enzymes for Dogs and Cats (12 oz) Powder (Made in U.S.A). Pancreatin 10X for Dogs and Cats Contain Pancreatic Enzyme, High Strength, Low Odor.(10x Porcine Pancreatin)
Pet Health Pharma

PancreaMax 10x Pancreatic Enzymes for Dogs and Cats (12 oz) Powder (Made in U.S.A). Pancreatin 10X for Dogs and Cats Contain Pancreatic Enzyme, High Strength, Low Odor.(10x Porcine Pancreatin)

Why we love it
  • Highest potency for optimal digestion.
  • Supports nutrient absorption effectively.
  • Made in the USA with care.
Main Highlights
  • ❤️Highest Potency Available – 10x Porcine Pancreatic Enzyme Powder
  • ❤️Maximum Enzyme Levels To Support Digestion Of Fats, Proteins & Carbohydrates
  • ❤️Contains Lipase, Amylase & Protease Digestive Enzymes For Nutrient Absorption
  • ❤️Acetone-Free | Dust-Free | Low-Odor Formulation for more palatable product with chicken flavor.
  • ❤️Our Pancreatin is proudly made in the USA and is manufactured to human grade standards
  • ❤️2.8g SCOOP ----🥄 🥄🥄🥄 SCOOP included 🥄in the CONTAINER.
  • ❤️Save Money with per meal/per cup of food. (meal = up to 2.5 cups of food)
  • ❤️The only 10x formulation with 2.8 g dosing per meal/per-cup of food.
  • ❤️Produced & Packaged In GMP Compliant Facilities
  • ❤️Only intended for use in dogs that require these enzymes to support proper digestive activity.
9.3
Superb
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4
9.2
Superb
Pancreatin 10X - Pancreatic enzymes for Dogs and Cats (Made in USA) High Strength | Low Odor |10oz (285g)
Paw Vitality LLC

Pancreatin 10X - Pancreatic enzymes for Dogs and Cats (Made in USA) High Strength | Low Odor |10oz (285g)

Why we love it
  • Supports healthy weight maintenance.
  • Enhances overall pet health.
  • High potency for cost savings.
Main Highlights
  • Pancreatin helps pets with exocrine pancreatic insufficiency (EPI) who lack the necessary digestive enzymes (amylase, lipase, protease) produced by the pancreas, hindering proper digestion. Pancreatin Addresses this issue by supplementing those digestive enzymes helping your pet breakdown and absorb their food which in turn helps them get the proper nutrition they need.
  • Our Pancreatin is proudly made in the USA and is manufactured to human grade standards.
  • Pancreatin 10X is high strength and high potency. This means less is required per meal which translates into savings for you.
  • Low Odor and Acetone free formulation.
  • Supports Weight Maintenance - Improved digestion and nutrient absorption through pancreatin supplementation can help prevent weight loss, allowing pets to maintain a healthy body weight.
  • Enhances Overall Health - By addressing the underlying digestive enzyme deficiency, pancreatin supplementation supports the overall health and well-being of pets, improving their energy levels, coat condition, and vitality.
9.2
Superb
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5
9.2
Superb
Pancreatic Enzymes for Dogs (Thomas Pet Bio Case Same Formula) - Lots of Love Pet Products - 12 Oz Powder
LOTS OF LOVE PET PRODUCTS

Pancreatic Enzymes for Dogs (Thomas Pet Bio Case Same Formula) - Lots of Love Pet Products - 12 Oz Powder

Why we love it
  • High potency enzyme support.
  • Aids nutrient absorption efficiency.
  • Promotes healthy digestive function.
Main Highlights
  • THOMAS PET BIO CASE (THOMAS LABS) - Same Formula as Thomas Pet Bio Case. 100% Guarantee
  • Biocase V - High potency, pancreatic enzyme powder formulated for use as a digestive supplement to support enzyme replacement needs
  • Earlier Bio Case Plus - Contains high levels of enzymes that assist the pancreas in the breakdown of carbohydrates, proteins, and fats
  • Supports the absorption of nutrients, helps maintain a healthy intestinal tract, & supports pet digestion
  • Contains beneficial digestive enzymes to aid digestion and support the immune system
  • Provides pancreatic enzymes & other elements necessary for proper digestion
9.2
Superb
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6
9.0
Superb
Pancreatic Enzyme for Dogs - Creati-Care 10x Dog Digestive Enzymes Powder with Vitamins Restore Normal Weight, Supports Pancreatin Issues Relieves Digestive Stress - 12 oz
Gateway Pet Products

Pancreatic Enzyme for Dogs - Creati-Care 10x Dog Digestive Enzymes Powder with Vitamins Restore Normal Weight, Supports Pancreatin Issues Relieves Digestive Stress - 12 oz

Why we love it
  • Supports overall health and wellness.
  • Veterinary recommended for safety.
  • Packed with essential vitamins.
Main Highlights
  • Pancreatin Enzymes at the ultimate and preferred levels. Veterinary recommended.
  • Vitamin A added. Helps preserve eyesight, lowers the risk if certain cancers and helps support the immune system.
  • Vitamin D added. Helps with weight management and oral health while strengthening bones and muscle.
  • Vitamin E added to fight against cognitive decline, improves lung function and helps provide healthy skin.
9.0
Superb
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7
8.9
Excellent
Pancreatic Enzymes for Dogs – 10X Pancreatin Digestive Enzyme Powder – Dog EPI Supplement for Pancreas Support – Helps Restore Weight, Improve Digestion & Relieve GI Stress – 11.99 oz – Vet Formulated
VivaElixir

Pancreatic Enzymes for Dogs – 10X Pancreatin Digestive Enzyme Powder – Dog EPI Supplement for Pancreas Support – Helps Restore Weight, Improve Digestion & Relieve GI Stress – 11.99 oz – Vet Formulated

Why we love it
  • High-potency digestive enzyme support.
  • Restores healthy weight and digestion.
  • Easy-to-mix, vet-formulated powder.
Main Highlights
  • ✅ High-Potency Pancreatic Enzymes for Dogs - Formulated with Pancreatin 10X, this powerful digestive enzyme powder supports dogs with Exocrine Pancreatic Insufficiency (EPI), helping to improve nutrient absorption and reduce undigested food.
  • ✅ Restores Digestive Health & Normal Weight - Ideal for dogs with weight loss, diarrhea, or nutrient deficiencies due to enzyme deficiency. This EPI dog supplement helps restore healthy digestion and promotes healthy weight gain.
  • ✅ Supports Pancreas Function & Gut Balance - Includes probiotics and digestive enzymes to support pancreatic health, reduce digestive stress, and promote a healthy intestinal tract in dogs of all sizes.
  • ✅ Easy-to-Mix Digestive Enzyme Powder - This odor-controlled powder blends easily into your dog's food for daily use. No messy pills or complicated dosing—just simple, vet-formulated support.
  • ✅ Vet-Formulated & Made in the USA - Crafted in a GMP-certified facility with high-quality, USP-grade ingredients. 100% natural, non-GMO, and safe for long-term use in dogs with chronic digestive issues.
8.9
Excellent
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8
8.7
Excellent
Pan-tenex | 10x Digestive Enzymes for Dogs - 4 Ounces (113 Grams)
Pan-tenex

Pan-tenex | 10x Digestive Enzymes for Dogs - 4 Ounces (113 Grams)

Why we love it
  • Highest potency for optimal digestion.
  • Supports nutrients absorption effectively.
  • Cost-efficient dosing for meals.
Main Highlights
  • Highest Potency Available – 10x Porcine Pancreatic Enzyme Powder
  • Maximum Enzyme Levels To Support Digestion Of Fats, Proteins & Carbohydrates
  • Contains Lipase, Amylase & Protease Digestive Enzymes For Nutrient Absorption
  • Acetone-Free | Dust-Free | Low-Odor Formulation
  • Dosed Per Meal, Not Per Cup Of Food | Use Less & Save More
8.7
Excellent
Amazon Logo
9
8.7
Excellent
Zhibenon Pancreatic Enzyme Powder for Dogs - 10X High Potency Pancreatin Supplement (285g/10oz) - Supports Nutrient Absorption, Improves Digestive Health for Pets
Zhibenon

Zhibenon Pancreatic Enzyme Powder for Dogs - 10X High Potency Pancreatin Supplement (285g/10oz) - Supports Nutrient Absorption, Improves Digestive Health for Pets

Why we love it
  • High Potency Digestion Support.
  • Designed for EPI Pets.
  • Gentle, Pure Formula.
Main Highlights
  • 10X High Potency for Better Digestion:10X concentrated pancreatin (amylase 672,000 USP, protease 616,000 USP, lipase 102,000 USP) , powder form mixes uniformly with food—higher absorption ideal for pets with EPI.
  • Designed for EPI Pets: supports healthy nutrient absorption to promote weight gain and restore your pet's energy levels, without adding unnecessary flavorings or binders.
  • Fits All Pets: Our digestive enzymes work for dogs of over six weeks of age, all breeds, all sizes (puppies/kittens to large adults).
  • Gentle & Pure Formula: Made with high-quality porcine pancreatin, no artificial additives, preservatives, or flavor enhancers, great for pets with sensitive guts or picky eating.
  • Easy & Mess-Free to Use: Mix with moistened food, let stand 15 mins before feeding, 285g/10oz packaging ensures long-lasting use.
8.7
Excellent
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10
8.7
Excellent
CK Formulations | Pancretase Digestive Enzymes | 10x Pancreatin | Pancreatin for Dogs and Cats | Pancreatic Enzyme | Great for Pets with EPI
CK Formulations

CK Formulations | Pancretase Digestive Enzymes | 10x Pancreatin | Pancreatin for Dogs and Cats | Pancreatic Enzyme | Great for Pets with EPI

Why we love it
  • High potency for better digestion.
  • Supports pets with pancreatic issues.
  • Proceeds benefit animals in need.
Main Highlights
  • Pancretase is a high potency, 10X form of Pancreatin for dogs and cats.
  • Pancreatin contains 3 digestive enzymes: Amylase, Protease and Lipase. These 3 enzymes aid in the digestion and absorption of carbohydrates, proteins and fats. This is especially important for pets who have pancreatic insufficiencies and lack those enzymes. Without these enzymes, food and nutrients are not broken down and absorbed properly, potentially causing severe malnutrition.
  • Every batch of Pancretase is sent to an independent, third party lab for testing to ensure the purity and potency of every serving.
  • A portion of all proceeds go towards animal shelters, rescues and foster homes, who have Exocrine Pancreatic Insufficent (EPI) pets who are in need of Pancreatin.
8.7
Excellent
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