10 Best Laxatives For Constipation Suppositories of 2026

Last updated on 04/03/2026
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Best Choice
1
9.8
Exceptional
MiraLAX Laxative Powder, Gentle Constipation Relief for Adults, Stool Softener with PEG 3350, Nonstimulant Laxative, No Harsh Side Effects, Osmotic Laxative, 45 Dose
MiraLAX

MiraLAX Laxative Powder, Gentle Constipation Relief for Adults, Stool Softener with PEG 3350, Nonstimulant Laxative, No Harsh Side Effects, Osmotic Laxative, 45 Dose

Why we love it
  • Gentle hydration for your system.
  • No harsh side effects experienced.
  • Physician recommended for effectiveness.
Main Highlights
  • Works naturally with the water in your body: MiraLAX laxative powder gently unblocks your system by hydrating and softening your stool for occasional constipation relief
  • No harsh side effects: A laxative for constipation that doesn't cause gas, bloating, cramping, or sudden urgency
  • Nonstimulant: Cramp-free constipation relief for women and men that won’t disrupt your day; works naturally with the water in your body
  • #1 doctor-recommended OTC laxative: Recommended by physicians, gastroenterologists, and pharmacists for safe and effective constipation relief for adults
  • Unflavored, grit-free powder: Dissolves completely in any hot or cold beverage for a simple, stress-free experience
  • Free from sugar, preservatives, and gluten: Dependable and gentle laxative for women and men
9.8
Exceptional
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Best Value
2
9.7
Exceptional
Save 9%
Fleet Glycerin Suppositories for Constipation Relief, Fast and Effective Stimulant-Free Laxative with Aloe Vera, 100 Count Jar, Pack of 4
Fleet

Fleet Glycerin Suppositories for Constipation Relief, Fast and Effective Stimulant-Free Laxative with Aloe Vera, 100 Count Jar, Pack of 4

9% Off
Why we love it
  • Fast relief in 15 minutes.
  • Gentle and easy insertion.
  • Doctor-recommended for effectiveness.
Main Highlights
  • Fleet Laxative Glycerin Suppositories provide fast, effective relief from occasional constipation and irregularity in 15 minutes to 1 hour
  • Laxative glycerin suppository works with your body to help gently unblock your system by attracting water into the colon
  • Fleet suppositories' easy to use, lubricated gentle glide tips are uniquely cone-shaped and formulated with soothing aloe for easier insertion
  • Fleet Laxative Glycerin Suppositories are stimulant-free laxatives for constipation relief
  • Fleet is the number one doctor-recommended brand of enemas* and suppositories** *ProVoice Data 2/1/22 to 1/31/23; **IQVIA Survey, 5/1/23 to 4/30/24 and TABS, L52W thru 5/19/24
  • Contains 4 jars of Fleet Laxatives, Laxative Glycerin Suppositories for Adult Constipation, 100 suppositories each
9.7
Exceptional
Save 9%
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3
9.6
Superb
Pedia-Lax Liquid Glycerin Suppositories for Kids Ages 2-5, Gentle Constipation Relief Laxative for Children, 6 Count, Pack of 3
Pedia-Lax

Pedia-Lax Liquid Glycerin Suppositories for Kids Ages 2-5, Gentle Constipation Relief Laxative for Children, 6 Count, Pack of 3

Why we love it
  • Gentle relief for kids' constipation.
  • Fast-acting within 15-60 minutes.
  • Pediatrician-recommended for safety.
Main Highlights
  • Pedia-Lax Laxative Liquid Glycerin Suppositories provide gentle constipation relief for kids in 15-60 minutes
  • Liquid glycerin suppositories are designed for kids ages 2-5 who experience occasional constipation
  • Small, kid-sized suppositories for constipation are sodium-free and won’t upset the digestive system
  • Pedia-Lax is the number 1 pediatrician-recommended children's laxative brand* *IQVIA, using the ProVoice Survey December 1, 2021 to November 30, 2022)
  • Contains 1 jar of Pedia-Lax Laxative Glycerin Suppositories, 12 count; FSA- and HSA-eligible product in the U.S.
9.6
Superb
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4
9.4
Superb
Dulcolax Stimulant Laxative Medicated Suppositories, Predictable & Effective Constipation Relief, Bisacodyl 10 mg, 28 Count, 2 pk
Dulcolax

Dulcolax Stimulant Laxative Medicated Suppositories, Predictable & Effective Constipation Relief, Bisacodyl 10 mg, 28 Count, 2 pk

Why we love it
  • Fast relief in minutes.
  • Targets the source directly.
  • Doctor recommended brand.
Main Highlights
  • Includes: Two (2) 28-count boxes of Dulcolax medicated stimulant laxative suppositories
  • Works fast: Dulcolax suppositories provide fast relief from constipation in as little as 15 to 60 minutes
  • Targets the source: Suppositories deliver the active ingredient directly into the rectum for localized relief where it's needed
  • Effective active ingredient: Dulcolax medicated laxative suppositories are made with 10 mg bisacodyl, which stimulates your gut muscles to move things out
  • On-the-go relief: Pack these compact laxative suppositories in your travel essentials to help you get back to being regular when stress and overindulgence slow you down
  • Doctor recommended: Dulcolax is the No. 1 doctor-recommended brand among OTC stimulant laxative brands
  • Comfort-shaped: These laxative suppositories are made to comfortably insert and retain to give you the relief you need
9.4
Superb
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5
9.3
Superb
Save 11%
NeilMed Bisacodyl Laxative Suppositories, Gentle Constipation Relief, Fast Acting, indivudally Wrapped hygienic Packaging, Bisacodyl 10 mg, Predictable Relief, 30 ct
NeilMed

NeilMed Bisacodyl Laxative Suppositories, Gentle Constipation Relief, Fast Acting, indivudally Wrapped hygienic Packaging, Bisacodyl 10 mg, Predictable Relief, 30 ct

11% Off
Why we love it
  • Quick relief from constipation.
  • Fast-acting, effective formula.
  • Pain-free, easy application.
Main Highlights
  • PROMPT, PREDICTABLE RELIEF FROM CONSTIPATION: NeilMed bisacodyl suppositories have an efficient laxative formula that can help provide quick relief from occasional constipation. Our suppositories may help alleviate discomfort and pain so you can regain your vitality.
  • FAST-ACTING EFFECTIVE FORMULA: These suppositories for constipation contain a powerful active ingredient, bisacodyl 10mg USP, known for its amazing effect on constipation and discomfort by stimulating bowel movement in a natural way.
  • OPTIMAL RELIEF: With the NeilMed suppositories, you can wave goodbye to the uncomfortable feeling caused by constipation or irregularity. This formula provides constipation relief for adults as quickly as 15 minutes to an hour.
  • PAIN FREE -EASY APPLICATION: Our laxatives for constipation are carefully shaped to ensure easy insertion without creating any discomfort or pain. They have a smooth surface and a comfortable shape that makes the insertion simply effortless and pain-free.
  • ACTIVE INGREDIENT BISACODYL: The NeilMed constipation relief suppositories come in a convenient and affordable pack of 30 pieces. The package is compact and easy to carry, so you can intervene in time in case of an emergency anywhere you are. Each suppository contains 10 mg of Bisacodyl, a stimulant laxative, to provide you with quick and effective relief of occasional constipation.
9.3
Superb
Save 11%
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6
9.1
Superb
Save 37%
Dulcolax Stimulant Laxative Medicated Suppositories, Predictable & Effective Constipation Relief, Bisacodyl 10 mg, 28 Count, Stimulant Laxatives
Dulcolax

Dulcolax Stimulant Laxative Medicated Suppositories, Predictable & Effective Constipation Relief, Bisacodyl 10 mg, 28 Count, Stimulant Laxatives

37% Off
Why we love it
  • Fast relief in 15 minutes.
  • Targets relief where needed.
  • Doctor recommended for effectiveness.
Main Highlights
  • Includes: One (1) 28-count box of Dulcolax medicated stimulant laxative suppositories
  • Works fast: Dulcolax suppositories provide fast relief from constipation in as little as 15 to 60 minutes
  • Targets the source: Suppositories deliver the active ingredient directly into the rectum for localized relief where it's needed
  • Effective active ingredient: Dulcolax medicated laxative suppositories are made with 10 mg bisacodyl, which stimulates your gut muscles to move things out
  • On-the-go relief: Pack these compact laxative suppositories in your travel essentials to help you get back to being regular when stress and overindulgence slow you down
  • Doctor recommended: Dulcolax is the No. 1 doctor-recommended brand among OTC stimulant laxative brands
  • Comfort-shaped: These laxative suppositories are made to comfortably insert and retain to give you the relief you need
9.1
Superb
Save 37%
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7
9.0
Superb
Fleet Liquid Glycerin Suppositories for Constipation Relief, Fast and Effective Stimulant-Free Laxative, 4 Bottles per Pack, 7.5 mL Each, Pack of 3
Fleet

Fleet Liquid Glycerin Suppositories for Constipation Relief, Fast and Effective Stimulant-Free Laxative, 4 Bottles per Pack, 7.5 mL Each, Pack of 3

Why we love it
  • Fast relief within an hour.
  • Gentle on your system.
  • Doctor-recommended trusted brand.
Main Highlights
  • Fleet Liquid Glycerin Suppositories provide fast, effective relief from occasional constipation and irregularity in 15 minutes to 1 hour
  • Liquid Glycerin Suppository may provide relief from GLP-1 related constipation, consult your doctor
  • Easy-to-use liquid suppositories come with a mess-free suppository applicator and lubricated gentle glide tip for gentle constipation relief
  • Fleet Liquid Glycerin Suppositories are stimulant-free laxatives for constipation relief
  • Fleet is the number one doctor-recommended brand of enemas* and suppositories** *ProVoice Data 2/1/22 to 1/31/23; **IQVIA Survey, 5/1/23 to 4/30/24 and TABS, L52W thru 5/19/24
9.0
Superb
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8
8.9
Excellent
AVEDANA Bisacodyl Laxative Suppository | USP 10mg for Fast, Gentle Constipation Relief | Comfort-Shaped, Pack of 16 Suppositories
AVEDANA

AVEDANA Bisacodyl Laxative Suppository | USP 10mg for Fast, Gentle Constipation Relief | Comfort-Shaped, Pack of 16 Suppositories

Why we love it
  • Quick relief from constipation.
  • Effective and natural formula.
  • Comfortable and easy to use.
Main Highlights
  • Optimal Solution: The Avedana bisacodyl suppositories have an efficient laxative formula that can help provide quick relief from occasional constipation. Our suppositories may help alleviate discomfort and pain so you can regain your vitality.
  • Effective Formula: These suppositories for constipation contain a powerful active ingredient, bisacodyl 10mg USP, known for its amazing effect on constipation and discomfort by stimulating bowel movement in a natural way.
  • Fast Relief: With the Avedana suppositories, you can wave goodbye to the uncomfortable feeling caused by constipation or irregularity. This formula provides constipation relief for adults as quickly as 15 minutes to an hour.
  • Comfort-Shaped: Our laxatives for constipation are carefully shaped to ensure easy insertion without creating any discomfort or pain. They have a smooth surface and a comfortable shape that makes the insertion simply effortless and pain-free.
  • What You Get: The Avedana constipation relief suppositories come in a convenient and affordable pack of 16 pieces. The package is compact and easy to carry, so you can intervene in time in case of an emergency anywhere you are.
8.9
Excellent
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9
8.8
Excellent
AVEDANA USP 2g Glycerin Laxatives Suppository – 100 Adult Size Laxative Suppositories for Men and Women – Fast and Gentle Relief Suppositories for Constipation – Comfortable Shape Adult Suppository
AVEDANA

AVEDANA USP 2g Glycerin Laxatives Suppository – 100 Adult Size Laxative Suppositories for Men and Women – Fast and Gentle Relief Suppositories for Constipation – Comfortable Shape Adult Suppository

Why we love it
  • Fast relief from discomfort.
  • Gentle and safe solution.
  • Ergonomic design for easy use.
Main Highlights
  • The Ideal Choice: Say goodbye to pain and discomfort with the Avedana constipation relief suppositories! Our special formula can bring fast and gentle relief that will restore your inner balance and make you feel better again.
  • Fast and Effective: These laxative suppositories can help relieve discomfort within minutes from insertion. Our suppositories may help alleviate constipation symptoms and stimulate bowel movement in 15 minutes to one hour.
  • Gentle Relief: The Avedana glycerin suppositories are an efficient and safe solution to relieve occasional constipation. They have a powerful laxative effect that delivers gentle and fast relief and a soothing effect. Customer Rated No. 1 for Colon
  • Ergonomic Shape: We designed these suppositories for constipation with your health and safety in mind. That is why the Avedana suppositories, compared with other similar products on the market, have a unique shape for easy, painless insertion.
  • How It Works: Our suppository laxative pack is formulated with special ingredients and 2g of glycerin per capsule for maximum benefits. Glycerin absorbs water and can help stimulate bowel movement, so make sure to drink plenty of water for efficient results.
8.8
Excellent
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10
8.7
Excellent
Save 18%
Fleet Glycerin Suppositories for Constipation Relief, Fast and Effective Stimulant-Free Laxative with Aloe Vera, 50 Count Jar, Pack of 3
Fleet

Fleet Glycerin Suppositories for Constipation Relief, Fast and Effective Stimulant-Free Laxative with Aloe Vera, 50 Count Jar, Pack of 3

18% Off
Why we love it
  • Fast relief within an hour.
  • Gentle and stimulant-free formula.
  • Easy insertion with lubricated tips.
Main Highlights
  • Fleet Laxative Glycerin Suppositories provide fast, effective relief from occasional constipation and irregularity in 15 minutes to 1 hour
  • Laxative glycerin suppository works with your body to help gently unblock your system by attracting water into the colon
  • Fleet suppositories' easy to use, lubricated gentle glide tips are uniquely cone-shaped and formulated with soothing aloe for easier insertion
  • Fleet Laxative Glycerin Suppositories are stimulant-free laxatives for constipation relief
  • Fleet is the number one doctor-recommended brand of enemas* and suppositories** *ProVoice Data 2/1/22 to 1/31/23; **IQVIA Survey, 5/1/23 to 4/30/24 and TABS, L52W thru 5/19/24
8.7
Excellent
Save 18%
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