10 Best Kleenex Tissues Boxes of 2026

Last updated on 04/04/2026
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Best Choice
1
9.8
Exceptional
Kleenex Professional Facial Tissue, Bulk (21270), 2-Ply, White, Upright Cube Boxed Format, Designed for Business (90 Tissues/Box, 36 Boxes, 3,240 Sheets/Case)
Kleenex

Kleenex Professional Facial Tissue, Bulk (21270), 2-Ply, White, Upright Cube Boxed Format, Designed for Business (90 Tissues/Box, 36 Boxes, 3,240 Sheets/Case)

Why we love it
  • Soft and strong for comfort.
  • Trusted brand for quality.
  • Eco-friendly and responsibly sourced.
Main Highlights
  • 90 Tissues/Box; 36 Kleenex Professional Facial Tissue Boxes/Case; 3,240 Tissues/Case; 2-Ply; White; Upright Facial Tissue Cube Boxes for Business
  • Kleenex is the world's number one facial tissue brand, trusted by more consumers than any other
  • Each Kleenex tissue is 2-ply, absorbent, soft and strong
  • The Signal Sheet keeps you ahead of run-outs (final 10 tissues are colored light blue instead of white, so you'll know it's time to replace the box)
  • FSC certified; FSC mix paper supporting responsible forestry
9.8
Exceptional
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🛡️Trusted by 100M+ UsersWhy?
Best Value
2
9.7
Exceptional
Kleenex® Professional Facial Tissue, Bulk (21271), 2-Ply, White, Upright Cube Boxed Format, Designed for Business (90 Tissues/Box, 6 Bundles of 6 Boxes, 3,240 Sheets/Case)
Kleenex

Kleenex® Professional Facial Tissue, Bulk (21271), 2-Ply, White, Upright Cube Boxed Format, Designed for Business (90 Tissues/Box, 6 Bundles of 6 Boxes, 3,240 Sheets/Case)

Why we love it
  • Trusted brand ensures quality care.
  • Soft and absorbent for comfort.
  • Signal Sheet prevents run-out surprises.
Main Highlights
  • 90 Tissues/Box; 36 Boxes/Case (6 Bundles of 6 Boxes); Kleenex Professional Facial Tissue; 3,240 Tissues/Case; 2-Ply; White; Upright Facial Tissue Cube Boxes for Business
  • Kleenex is the #1 brand of facial tissue in North America, trusted by more consumers than any other.
  • Each Kleenex tissue is 2-ply, absorbent, soft and strong; Signal Sheet keeps you ahead of run-outs (final 10 tissues are colored light blue instead of white, so you'll know it's time to replace the box)
  • Compact cube box fits easily on reception counters, desks, treatment rooms and break areas without clutter; bulk case format supports predictable stocking for small teams without dedicated facilities staff
  • FSC certified; FSC mix paper supporting responsible forestry
9.7
Exceptional
Amazon Logo
3
9.6
Superb
KLEENEX Facial Tissue in Boutique Pop-Up Box, 95/Box, 36 Boxes/Carton
Kimberly-Clark

KLEENEX Facial Tissue in Boutique Pop-Up Box, 95/Box, 36 Boxes/Carton

Why we love it
  • Elegant design enhances decor.
  • Signal feature ensures timely replacement.
  • Superior quality for everyday use.
Main Highlights
  • POP-UP* dispenser box with SIGNAL* feature: Colored tissues indicate new box is needed. The elegant platinum s
  • wirl design on the BOUTIQUE* box enhances any decor. Superior product performance and prem
  • ium quality. Stock up and save! Tissue Type: Facial Number of Plies: 2 Number of Sheets: 95 per bo
  • x. Unit of Measure : Carton
  • *** Please Note: Photo may not represent actual item, refer to full description for detailed accurate product information
9.6
Superb
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4
9.5
Superb
Save 17%
Kleenex Professional Facial Tissue, Bulk (21400), 2-Ply, White, Flat Boxed Format, Designed for Business (100 Tissues/Box, 36 Boxes, 3,600 Sheets/Case)
Kleenex

Kleenex Professional Facial Tissue, Bulk (21400), 2-Ply, White, Flat Boxed Format, Designed for Business (100 Tissues/Box, 36 Boxes, 3,600 Sheets/Case)

17% Off
Why we love it
  • Trusted top brand worldwide.
  • Ultra-soft, absorbent tissues.
  • Eco-friendly FSC certified product.
Main Highlights
  • 100 Tissues/Box; 36 Boxes of Kleenex Professional Facial Tissue/Case; 3,600 Tissues/Case; 2-Ply; White; Flat Facial Tissue Boxes for Business
  • Kleenex is the #1 brand of facial tissue in North America, trusted by more consumers than any other
  • Each Kleenex tissue is 2-ply, absorbent, soft and strong
  • Each tissue features smart innovations like an ultra-soft feel
  • FSC certified; FSC mix paper supporting responsible forestry
9.5
Superb
Save 17%
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5
9.5
Superb
Save 10%
Kleenex® Professional Facial Tissue, Bulk (03076), 2-Ply, White, Flat Facial Tissue Boxes for Business, Convenience Case (125 Tissues/Box, 12 Boxes/Case, 1,500 Tissues/Case)
Kleenex

Kleenex® Professional Facial Tissue, Bulk (03076), 2-Ply, White, Flat Facial Tissue Boxes for Business, Convenience Case (125 Tissues/Box, 12 Boxes/Case, 1,500 Tissues/Case)

10% Off
Why we love it
  • Trusted brand for quality tissues.
  • Ultra-soft and absorbent feel.
  • FSC certified for sustainability.
Main Highlights
  • 125 Tissues/Box; 12 Boxes of Kleenex Professional Facial Tissue/Case; 1,500 Tissues/Case; 2-Ply; White; Flat Facial Tissue Boxes for Business; Convenience Case
  • Kleenex is the #1 brand of facial tissue in North America, trusted by more consumers than any other.
  • Each Kleenex tissue is 2-ply, absorbent, soft and strong
  • Slim case and versatile box design fit easily into desks, counters and cabinets, providing a clean, professional presentation with simple, space-efficient stocking.
  • FSC certified; FSC mix paper supporting responsible forestry
9.5
Superb
Save 10%
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6
9.4
Superb
Save 6%
Kleenex Ultra Soft Facial Tissues - Pack of 12 Cube Tissue Boxes
Kleenex

Kleenex Ultra Soft Facial Tissues - Pack of 12 Cube Tissue Boxes

6% Off
Why we love it
  • Gentle on sensitive skin.
  • Silky soft for luxurious comfort.
  • Trusted brand you can rely on.
Main Highlights
  • Gentle for your skin - Sick of rough tissues making your cold feel even worse? Give your skin the comfort you deserve with Kleenex Ultra Soft tissues.
  • Silky soft and luxurious - Kleenex Ultra Soft tissues are one of the UK's softest facial tissues. Designed with luxury in mind Kleenex Ultra Soft Tissues will leave your skin feeling beautiful
  • From a brand you can trust – Kleenex Ultra Soft tissues are made by Kimberly-Clark, the manufacturer of Andrex toilet roll and Huggies baby wipes - so you can be sure that you’re buying the highest quality product.
  • A sustainable choice – Out tissue boxes now made with paper baffle meaning they are fully recyclable, making Kleenex UltraSoft Tissues a sustainable choice.
  • Buy a pack of 12 cube boxes - Bulk buy 12 cube boxes of our tissues so you and your family never run out when you need them most.
9.4
Superb
Save 6%
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7
9.2
Superb
Kleenex Ultra Soft Facial Tissues, 8 Cube Boxes, 80 Tissues per Box, 3-Ply, Packaging May Vary
Kleenex

Kleenex Ultra Soft Facial Tissues, 8 Cube Boxes, 80 Tissues per Box, 3-Ply, Packaging May Vary

Why we love it
  • Ultimate comfort for every moment.
  • Hypoallergenic for sensitive skin.
  • Strong and mess-free alternatives.
Main Highlights
  • WHAT'S INCLUDED — 8 cube boxes of Kleenex Ultra Soft Facial Tissues, 3-Ply, 80 tissues per box (640 tissues total)
  • FOR THE BIG AND LITTLE MOMENTS — Back to school season, allergy season, holiday season, graduation season, and every season in between, Kleenex Ultra Soft is there for it all
  • SILKY SOFTNESS— These facial tissues are made with 3 layers of silky-soft strength that’s gentle on watery eyes and runny noses for an extra bit of comfort when you need it
  • ALLERGIST APPROVED — Our tissues are hypoallergenic, dermatologist tested, and allergist approved
  • SAVE YOUR TOILET PAPER — When it comes to blowing your nose, Kleenex has got you covered. Our tissues are made with Clean Shield that contains the mess better than the leading value toilet paper
  • THE #1 ULTRA TISSUE* — We’re the #1 ultra tissue* for a reason. Kleenex Ultra Soft comforts skin and helps protect hands with every tissue (*among national brands)
9.2
Superb
Amazon Logo
8
9.1
Superb
Kleenex Ultra Soft Facial Tissues, 8 Flat Boxes, 180 Tissues per Box, 3-Ply, Packaging May Vary
Kleenex

Kleenex Ultra Soft Facial Tissues, 8 Flat Boxes, 180 Tissues per Box, 3-Ply, Packaging May Vary

Why we love it
  • Ultra-soft for ultimate comfort.
  • Perfect for every occasion.
  • Allergist approved for sensitive skin.
Main Highlights
  • WHAT'S INCLUDED — 8 flat boxes of Kleenex Ultra Soft Facial Tissues, 3-Ply, 180 tissues per box (1,440 tissues total)
  • FOR THE BIG AND LITTLE MOMENTS — Back to school season, allergy season, holiday season, graduation season, and every season in between, Kleenex Ultra Soft is there for it all
  • SILKY SOFTNESS— These facial tissues are made with 3 layers of silky-soft strength that’s gentle on watery eyes and runny noses for an extra bit of comfort when you need it
  • ALLERGIST APPROVED — Our tissues are hypoallergenic, dermatologist tested, and allergist approved
  • SAVE YOUR TOILET PAPER — When it comes to blowing your nose, Kleenex has got you covered. Our tissues are made with Clean Shield that contains the mess better than the leading value toilet paper
  • THE #1 ULTRA TISSUE* — We’re the #1 ultra tissue* for a reason. Kleenex Ultra Soft comforts skin and helps protect hands with every tissue (*among national brands)
9.1
Superb
Amazon Logo
9
9.0
Superb
Save 16%
Kleenex Trusted Care Facial Tissues, 8 Flat Boxes, 200 Tissues per Box, 2-Ply, Packaging May Vary
Kleenex

Kleenex Trusted Care Facial Tissues, 8 Flat Boxes, 200 Tissues per Box, 2-Ply, Packaging May Vary

16% Off
Why we love it
  • Soft and strong for comfort.
  • Stylish designs for every home.
  • Convenient delivery right to door.
Main Highlights
  • WHAT'S INCLUDED — 8 flat boxes of Kleenex Trusted Care Facial Tissues, 2-Ply, 200 tissues per box (1,600 tissues total)
  • THE ORIGINAL SOFT & STRONG TISSUE — These facial tissues are made with same the trusted softness and strength that Kleenex is known for
  • SAVE YOUR TOILET PAPER — When it comes to blowing your nose, Kleenex has got you covered. Our tissues are made with Clean Shield that contains the mess better than the leading value toilet paper
  • YOUR EVERYDAY TISSUE — As the #1 everyday facial tissue*, Kleenex is perfect to use during allergy season, back-to-school season, and cold and flu season (*among national brands)
  • 2 LAYERS, 2 BENEFITS — Our facial tissues are thick, absorbent, and made with 2 strong layers to help keep hands clean
  • PERFECT FOR ANY HOME — Our Kleenex tissues boxes come in various stylish designs that complement your home décor (packaging may vary)
9.0
Superb
Save 16%
Amazon Logo
10
9.0
Superb
Kleenex Lotion Facial Tissues with Coconut Oil, 8 Cube Boxes, 80 Tissues Per Box, 3-Ply
Kleenex

Kleenex Lotion Facial Tissues with Coconut Oil, 8 Cube Boxes, 80 Tissues Per Box, 3-Ply

Why we love it
  • Moisturizing formula for comfort.
  • Stylish designs for any décor.
  • Dermatologist-tested for gentle care.
Main Highlights
  • WHAT'S INCLUDED — 8 boxes of Kleenex Lotion 3-Ply Facial Tissues with Coconut Oil & Aloe, 80 tissues per box (640 tissues total)
  • BE PREPARED FOR SICK DAYS — We know we can't prevent sick days, but Kleenex can help you through them by moisturizing your skin to help prevent skin irritation
  • 3 BENEFITS IN 1 TISSUE — Kleenex lotion facial tissues are designed to soothe and moisturize skin while protecting your hands, offering comprehensive care in every sheet
  • SAVE YOUR TOILET PAPER — When it comes to blowing your nose, Kleenex has got you covered. Our tissues are made with Clean Shield that contains the mess better than the leading value toilet paper
  • MADE WITH LOTION— These facial tissues are dermatologist-tested and infused with coconut oil and aloe
  • PERFECT FOR ANY HOME — Our Kleenex tissues boxes come in various stylish designs that complement your home décor (packaging may vary)
9.0
Superb
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Related Deals You Might Like for Kleenex Tissues Boxes

📊We scanned 158 products
🔍
We reviewed the most relevant Kleenex Tissues Boxes offers across Amazon and leading retailers, covering major brands and models. Our shortlist features trusted names like Kleenex, Kimberly-Clark, known for dependable quality and smart design.
⭐
To determine today's best Kleenex Tissues Boxes, we analyzed 791 real customer and expert reviews, focusing on satisfaction, real-world performance and long-term reliability. We also weigh each review's relevance, authenticity and freshness for a fair comparison.

Here's what we found:

🏆 #1
Kleenex Professional Facial Tissue, Bulk (21270), 2-Ply, White, Upright Cube Boxed Format, Designed for Business (90 Tissues/Box, 36 Boxes, 3,240 Sheets/Case)

Our overall winner is Kleenex Professional Facial Tissue, Bulk (21270), 2-Ply, White, Upright Cube Boxed Format, Designed for Business (90 Tissues/Box, 36 Boxes, 3,240 Sheets/Case) by Kleenex. It stands out for the right balance of quality, performance and value.

✨ What sets it apart:
✓Soft and strong for comfort.
✓Trusted brand for quality.
✓Eco-friendly and responsibly sourced.
💎 Best Value
Kleenex® Professional Facial Tissue, Bulk (21271), 2-Ply, White, Upright Cube Boxed Format, Designed for Business (90 Tissues/Box, 6 Bundles of 6 Boxes, 3,240 Sheets/Case)

The best value for most shoppers is Kleenex® Professional Facial Tissue, Bulk (21271), 2-Ply, White, Upright Cube Boxed Format, Designed for Business (90 Tissues/Box, 6 Bundles of 6 Boxes, 3,240 Sheets/Case) by Kleenex, with consistently high satisfaction across expert and customer reviews.

💰 Best Deal
Kleenex Professional Facial Tissue, Bulk (21400), 2-Ply, White, Flat Boxed Format, Designed for Business (100 Tissues/Box, 36 Boxes, 3,600 Sheets/Case)

The strongest deal right now for Kleenex Tissues Boxes is Kleenex Professional Facial Tissue, Bulk (21400), 2-Ply, White, Flat Boxed Format, Designed for Business (100 Tissues/Box, 36 Boxes, 3,600 Sheets/Case) at Kleenex, currently at 17% off.

🔄Our Kleenex Tissues Boxes ranking is updated regularly to reflect new releases and price changes—check back for the latest picks and deals.