10 Best Hangover Prevention Pills of 2026

Last updated on 05/01/2026
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Best Choice
1
9.8
Exceptional
ZBiotics — Feel Better After Drinking, Wake Up Refreshed, Science-Backed, Patented Probiotic for Easier Mornings, Travel-Friendly, 3-Pack of 0.47 Fl Oz Bottles
ZBiotics

ZBiotics — Feel Better After Drinking, Wake Up Refreshed, Science-Backed, Patented Probiotic for Easier Mornings, Travel-Friendly, 3-Pack of 0.47 Fl Oz Bottles

Why we love it
  • Better mornings after drinking.
  • Convenient travel-friendly size.
  • Powerful biotech for gut health.
Main Highlights
  • BETTER MORNINGS: Feel better the day after drinking with ZBiotics Pre-Alcohol Probiotic Drink
  • DRINK BEFORE DRINKING: 1) Drink ZBiotics, 2) Drink Responsibly, 3) Get plenty of rest.
  • HOW IT WORKS: When you drink, alcohol leaves behind a toxic byproduct called acetaldehyde in the gut. It’s this byproduct, not dehydration, that causes your rough next day. Invented by PhD scientists, ZBiotics breaks down acetaldehyde
  • CONVENIENT: 1 bottle is good for a whole day (lasts at least 18 hours in your gut), so if you're starting with brunch mimosas, you’re covered for whatever nighttime plans you have later. No refrigeration needed. TSA-friendly size for easy travel.
  • POWERFUL BIOTECHNOLOGY: ZBiotics has been genetically engineered to produce an enzyme to break down the alcohol byproduct acetaldehyde. It’s designed to work like your liver, but in your gut where you need it most.
9.8
Exceptional
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🛡️Trusted by 100M+ UsersWhy?
Best Value
2
9.7
Exceptional
H-PROOF The Anytime You Drink Vitamin, Liver Health & Immunity Support with Electrolytes, Milk Thistle, and Vitamins B & C - 40 Chewable Tablets (20 Servings), Vegan, Black Cherry
H-PROOF

H-PROOF The Anytime You Drink Vitamin, Liver Health & Immunity Support with Electrolytes, Milk Thistle, and Vitamins B & C - 40 Chewable Tablets (20 Servings), Vegan, Black Cherry

Why we love it
  • Supports healthy metabolism function.
  • Doctor-developed for optimal performance.
  • Nutrients tailored for post-drinking.
Main Highlights
  • WAKE UP FEELING BETTER THAN YOU SHOULD*: When you drink, your body produces enzymes to metabolize it in your liver. As we age, we produce fewer of these enzymes, and our metabolism slows down. The Anytime You Drink Vitamin promotes the enzymes that power metabolism. It also replenishes the vitamins and electrolytes you use up in that process & provides a ton of other good stuff that supports healthy brain, liver, and body function*
  • THE ONLY DOCTOR-DEVELOPED VITAMIN FOR WHEN YOU DRINK: Co-Founder and Chief Medical Officer Dr. Linda J. Kaplan MD, a board-certified medical doctor, combined her medical expertise with global scientific research to develop our double-patented 16-ingredient formula (Patent No. 11,096,904 and Patent No. 11,571,395). H-PROOF's The Anytime You Drink Vitamin supports metabolism, promotes liver health, and restores vital nutrients*
  • SCIENCE-SUPPORTED INGREDIENTS: Vitamin B6, Thiamin, Riboflavin, Niacin, Folate, Vitamin B12 and Pantothenic Acid promote enzymes that power metabolism. Antioxidants support the body's natural defenses against free radicals. Liver supporters DHM, Milk Thistle, Taurine, and L-Glutathione promote healthy liver function and metabolism. Vitamin C and Zinc support the immune system and cellular health. Electrolytes hydrate and help rebalance the brain, heart, and body.
  • VEGAN, SUGAR-FREE, GLUTEN-FREE, ZERO CALORIES: We take what we put into our bodies seriously, and we expect you do the same. All of our Vitamins are made in the USA in an FDA-registered facility that follows Good Manufacturing Practices, which is the highest standard achievable. Our Vitamins are tested for impurities and heavy metals.
  • EASY TO USE POST-DRINKS: Simply chew 2 tablets after your last drink! The number of chews you need depends on the number of drinks you have. Five or fewer drinks? Take 2 chews. More than five drinks? You'll need another 2 chews. And if needed, take 2 chews when you wake up in the morning.
9.7
Exceptional
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3
9.6
Superb
purple tree Post-Celebration Wellness Supplement | Liposomal Dihydromyricetin (DHM), L-Glutathione, Milk Thistle for Liver Support & Hydration | Electrolytes, B Vitamins, Willow Bark | 90 Pills
purple tree

purple tree Post-Celebration Wellness Supplement | Liposomal Dihydromyricetin (DHM), L-Glutathione, Milk Thistle for Liver Support & Hydration | Electrolytes, B Vitamins, Willow Bark | 90 Pills

Why we love it
  • Supports liver health effortlessly.
  • Top-quality herbal ingredients included.
  • Perfect for post-celebration recovery.
Main Highlights
  • Post-Drink Support for Responsible Drinkers: Purple Tree is a post-celebration wellness supplement designed to support your body after alcohol, celebrations, travel, or late nights. It helps promote normal liver function, hydration balance, and nutrient replenishment so you can wake up feeling clearer and more refreshed.*
  • Liposomal Advantage: Purple Tree is the only supplement featuring Liposomal DHM paired with Liposomal Glutathione and a synergistic blend of 10 additional nutrients, vitamins, and herbs. This advanced delivery system supports superior absorption and full-body wellness compared to regular DHM formulas.
  • Reset Your Mornings: Purple Tree’s lab-tested, clean ingredients include Milk Thistle, Willow Bark, and Dihydromyricetin (DHM) — a natural extract from the Japanese raisin tree, long valued in traditional wellness practices for its liver-supporting properties.
  • How It Works: Take tonight! Our purple pills can be taken with water any time before, during or after responsible drinking. Manufactured and tested in California at a GMP quality facility.
  • Over 500,000 Customers Worldwide: Purple Tree Labs is on a mission to empower 100 million responsible drinkers with premium, powerful ingredients that help balance fun, function and health. Purple Tree is the perfect addition to your vacation, beach, summer, music festivals, travel plan essentials and morning recovery. Hydrate wisely!
  • Feel Your Best: Designed for health-minded adults who celebrate responsibly, Purple Tree is the perfect post-celebration companion for bachelor and bachelorette parties, weddings, or weekend getaways, pre or post alcohol.
9.6
Superb
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4
9.5
Superb
Cheers Restore | Supplement with DHM + L-Cysteine | Feel Better After Drinking & Support Your Liver | 12 Doses | Dihydromyricetin, Cysteine, Prickly Pear, B-Vitamins, Ginger
Cheers

Cheers Restore | Supplement with DHM + L-Cysteine | Feel Better After Drinking & Support Your Liver | 12 Doses | Dihydromyricetin, Cysteine, Prickly Pear, B-Vitamins, Ginger

Why we love it
  • Proven success from Shark Tank.
  • Effective next-day recovery formula.
  • Transparent, high-quality ingredient list.
Main Highlights
  • AS SEEN ON SHARK TANK: Since our Shark Tank debut, we have delivered over 25 million better mornings.
  • BENEFITS YOU CAN FEEL: For next-day recovery, our capsules use a patented blend of DHM + Cysteine to tackle acetaldehyde exposure and GABA rebound — the main reasons why you feel bad after drinking.
  • NO PROPRIETARY BLENDS, NO B.S.: Rather than hiding our ingredients behind proprietary blends, we use patents to protect our formulas (Granted Patent US 10,736,870 B2). We prioritize quality & efficacy and are committed to providing full transparency into our products.
  • MOST DHM + CYSTEINE PER DOSE ON THE MARKET: DHM and Cysteine have been studied independently in reputable academic publications in relation to alcohol recovery and the liver. We’re proud to include the most DHM + cysteine on the market.
  • OVER 25 MILLION BETTER MORNINGS: Our products work as a system to help you feel great after drinking & support your alcohol-related health. For best results, pair Restore with our other products.
9.5
Superb
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5
9.3
Superb
Good Morning Hangover Pills | 88.89% Effective at Hangover Prevention in Clinical Trial | After Alcohol Aid with DHM, Milk Thistle, and Electrolytes to Help You Party smart. Cheers
Good Health Co

Good Morning Hangover Pills | 88.89% Effective at Hangover Prevention in Clinical Trial | After Alcohol Aid with DHM, Milk Thistle, and Electrolytes to Help You Party smart. Cheers

Why we love it
  • Ultimate after alcohol aid.
  • Restores vital nutrients quickly.
  • Clinically tested for effectiveness.
Main Highlights
  • Milk Thistle and DHM supplement blend provides the ultimate after alcohol aid, helping you to party smart and optimize for morning recovery, so there are no days wasted when you drink.
  • Electrolytes and Multivitamins help restore vital nutrients in the body, providing energy and focus to help you have a better morning. Packed with electrolytes for dehydration, the key to hangover prevention is hydration.
  • Trust clinically tested hangover pills —independently tested by the University of the Pacific in California and peer-reviewed in the National Institute of Health.
  • Liver Support: DHM (dihydromyricetin) and Milk Thistle support your body’s natural ability to handle alcohol and flush out toxins, helping promote morning recovery.
  • Say Cheers to our Travel Essentials: The perfect party kit to take to weddings, bachelorette parties, bachelor parties, cruise ships, vacations, happy hour, work, and social events.
  • Mental Fatigue: The worst part about drinking is waking up with headaches. Take two relief pills with a glass of water before bed to help with morning recovery. For enhanced results, take two pills before drinking.
  • Treating hangover relief is a complex science; you cannot wait until the morning after to deal with alcohol recovery, as the hope for no hangover has passed. Hangover prevention starts pre alcohol and during your sleep.
  • Supplement Facts: Magnesium reduces stress caused by alcohol. Vitamin C + E are antioxidants for immune system support. Vitamin B6 + B12 for energy metabolism and nerve function. Thiamin (Vitamin B1) helps energy metabolism + cell function.
9.3
Superb
Amazon Logo
7
9.0
Superb
Hellomush Rise and Shine DHM Hangover Prevention Pills - Best Hangover Relief & Recovery Supplement - Vitamins for Before & After Drinking - Individually Packaged for Convenience 30 Servings
Hellomush

Hellomush Rise and Shine DHM Hangover Prevention Pills - Best Hangover Relief & Recovery Supplement - Vitamins for Before & After Drinking - Individually Packaged for Convenience 30 Servings

Why we love it
  • Complete protection against hangovers.
  • Sleep-through relief overnight.
  • DHM supports detoxification naturally.
Main Highlights
  • Complete Protection: Advanced hangover prevention formula with DHM supplements; designed to support liver function and reduce alcohol's negative effects before drinking; clinically supported ingredients for best hangover prevention
  • Morning Recovery: Powerful hangover relief tablets that work while you sleep; our anti hangover pills target the root causes of hangover symptoms; wake up refreshed without the typical after drinking hangover recovery struggles
  • Science-Backed Formula: Our hangover pill contains dihydromyricetin (DHM); this natural compound helps process alcohol more efficiently; paired with essential drinking vitamins to support your body's natural detoxification process
  • Pre-Drinking Defense: Take as pre drinking hangover prevention before your first drink; our alcohol recovery supplements create a protective barrier; continue with pre alcohol hangover prevention throughout your evening for optimal results
  • Convenient Solution: Easy-to-swallow hangover capsules for on-the-go use; more effective than traditional hangover drinks; our no hangover products work with your body's natural processes; perfect companion for social occasions
9.0
Superb
Amazon Logo
8
8.8
Excellent
purple tree Post-Celebration Wellness Supplement | Liposomal Dihydromyricetin (DHM), L-Glutathione, Milk Thistle for Liver Support & Hydration | Electrolytes, B Vitamins, Willow Bark | 60 Capsules
purple tree

purple tree Post-Celebration Wellness Supplement | Liposomal Dihydromyricetin (DHM), L-Glutathione, Milk Thistle for Liver Support & Hydration | Electrolytes, B Vitamins, Willow Bark | 60 Capsules

Why we love it
  • Supports liver health effectively.
  • Replenishes key vitamins and electrolytes.
  • Perfect for post-celebration recovery.
Main Highlights
  • Post-Drink Wellness Supplement: Purple Tree is a post-celebration wellness supplement designed to support your body after alcohol, celebrations, travel, or late nights. It helps support normal liver function, hydration balance, and nutrient replenishment so you can wake up feeling clearer and more refreshed.*
  • Liposomal DHM + Liposomal Glutathione Formula: Purple Tree combines Liposomal Dihydromyricetin (DHM from Hovenia dulcis) with Liposomal Glutathione, Milk Thistle, electrolytes, and B vitamins. This advanced blend supports antioxidant activity and overall wellness.*
  • Enhanced Absorption Technology: Our liposomal delivery system helps protect key nutrients through digestion, supporting improved absorption compared to standard non-liposomal DHM supplements.*
  • Flexible Use – Before, During, or After Drinking: Take 2 capsules with water before, during, or after responsible drinking. Purple Tree will not prevent intoxication or alcohol poisoning. Manufactured and tested in California at an FDA-registered, GMP-certified facility.
  • Trusted by Over 500,000 Customers: With more than 7,000 reviews and 22 million doses sold, Purple Tree is a trusted supplement for vacations, festivals, weddings, bachelor and bachelorette parties, cruises, and social weekends.*
  • Clean, Lab-Tested Ingredients: Made with Liposomal DHM, Liposomal Glutathione, Milk Thistle, Willow Bark, Quercetin, Zinc, Magnesium, and methylated B12 (methylcobalamin). No artificial dyes. Natural purple color from sweet potato and spirulina.
  • Designed for Responsible Drinkers: Purple Tree is made for adults who enjoy social occasions but still want to feel their best the next day — helping support balance between fun, function, and health.*
8.8
Excellent
Amazon Logo
9
8.7
Excellent
SuperBonsai Super Recovery Capsules for Post Celebration and Morning Relief - All Natural Holistic Support - 3 Capsules Taken Before Drinking and an Optional Serving After (14 Servings)
SuperBonsai

SuperBonsai Super Recovery Capsules for Post Celebration and Morning Relief - All Natural Holistic Support - 3 Capsules Taken Before Drinking and an Optional Serving After (14 Servings)

Why we love it
  • Natural ingredients support recovery.
  • Scientifically proven for effective results.
  • Easy to take anywhere.
Main Highlights
  • 8 NATURAL SUPER INGREDIENTS - Start your day on the right note with SuperBonsai's doctor-formulated combination of Milk thistle, DHM, Korean Ginseng, Zinc, B vitamins, Ginger, Tumeric, and Prickly Pear. Our formula may help energize and revitalize you, transforming sluggish mornings into productive starts.
  • LIVER SUPPORT WITH DHM & MILK THISTLE - By creating this mix of natural ingredients, SuperBonsai has created Super Recovery with your recovery in mind. With all-natural ingredients known for their proven holistic health benefits, recovery after a weekend just got that much easier.
  • SCIENTIFICALLY FORMULATED FOR RESULTS - SuperRecovery's holistic and natural approach using Mother Nature's finest ingredients doesn't compete with other brands filled with additional chemicals.
  • QUALITY MATTERS - High quality doesn't stop with our ingredients, Super Recovery is manufactured in a GMP-certified facility & third-party tested. Every batch of Super Recovery is vegan, non-GMO, sugar-free, and free from artificial colors or additives.
  • EASY & CONVENIENT DOSING - Designed for your busy lifestyle, our capsules offer targeted support in an easy-to-take form. Just take 3 capsules before drinking and an optional serving after drinking. Get more out of your weekends and negate the bad side effects often associated with drinking with one easy-to-take supplement.
8.7
Excellent
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10
8.7
Excellent
Himalaya PartySmart, 12 Capsule Tube - Alcohol Breakdown Liver Support for a Better Morning After Drinking - Plant Based, Vegan, Non-GMO, Gluten Free, Clinically Studied
Himalaya

Himalaya PartySmart, 12 Capsule Tube - Alcohol Breakdown Liver Support for a Better Morning After Drinking - Plant Based, Vegan, Non-GMO, Gluten Free, Clinically Studied

Why we love it
  • Supports liver alcohol processing.
  • Promotes better mornings post-drinking.
  • Made with vegetarian herbal ingredients.
Main Highlights
  • One capsule for a better morning: Wake up in better spirits after a night of drinking with PartySmart; Our tube fits in your pocket or purse on a night out, best taken while drinking*
  • Supports alcohol metabolism: PartySmart helps metabolize alcohol more efficiently by accelerating the elimination of acetaldehyde, a byproduct of alcohol breakdown in the liver*
  • Gentle herbal ingredients: Formulated with clinically-studied, plant based ingredients like Andrographis, Chicory, Grapes, and Dates, without the harsh stimulants found in other night out products*
  • Adult party favors: Share the fun, PartySmart capsules are great party favors and wedding favors; Enjoy a night out together, skip the rough mornings
  • Thoughtfully crafted: PartySmart capsules are vegan and non-GMO without any gluten, dairy, soy, or corn; An ideal ayurvedic supplement for a better morning after drinking
8.7
Excellent
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Related Deals You Might Like for Hangover Prevention Pills

📊We scanned 273 products
🔍
We reviewed the most relevant Hangover Prevention Pills offers across Amazon and leading retailers, covering major brands and models. Our shortlist features trusted names like ZBiotics, H-PROOF, purple tree, Cheers, Good Health Co, OMRE, Hellomush, SuperBonsai, Himalaya, known for dependable quality and smart design.
⭐
To determine today's best Hangover Prevention Pills, we analyzed 1366 real customer and expert reviews, focusing on satisfaction, real-world performance and long-term reliability. We also weigh each review's relevance, authenticity and freshness for a fair comparison.

Here's what we found:

🏆 #1
ZBiotics — Feel Better After Drinking, Wake Up Refreshed, Science-Backed, Patented Probiotic for Easier Mornings, Travel-Friendly, 3-Pack of 0.47 Fl Oz Bottles

Our overall winner is ZBiotics — Feel Better After Drinking, Wake Up Refreshed, Science-Backed, Patented Probiotic for Easier Mornings, Travel-Friendly, 3-Pack of 0.47 Fl Oz Bottles by ZBiotics. It stands out for the right balance of quality, performance and value.

✨ What sets it apart:
✓Better mornings after drinking.
✓Convenient travel-friendly size.
✓Powerful biotech for gut health
💎 Best Value
H-PROOF The Anytime You Drink Vitamin, Liver Health & Immunity Support with Electrolytes, Milk Thistle, and Vitamins B & C - 40 Chewable Tablets (20 Servings), Vegan, Black Cherry

The best value for most shoppers is H-PROOF The Anytime You Drink Vitamin, Liver Health & Immunity Support with Electrolytes, Milk Thistle, and Vitamins B & C - 40 Chewable Tablets (20 Servings), Vegan, Black Cherry by H-PROOF, with consistently high satisfaction across expert and customer reviews.

💰 Best Deal
Himalaya PartySmart, 12 Capsule Tube - Alcohol Breakdown Liver Support for a Better Morning After Drinking - Plant Based, Vegan, Non-GMO, Gluten Free, Clinically Studied

The strongest deal right now for Hangover Prevention Pills is Himalaya PartySmart, 12 Capsule Tube - Alcohol Breakdown Liver Support for a Better Morning After Drinking - Plant Based, Vegan, Non-GMO, Gluten Free, Clinically Studied at Himalaya, currently at % off.

🔄Our Hangover Prevention Pills ranking is updated regularly to reflect new releases and price changes-check back for the latest picks and deals.