10 Best Suppository For Constipation of 2026

Last updated on 04/04/2026
Advertising disclosure
Best Choice
1
9.7
Exceptional
Dulcolax Stimulant Laxative Medicated Suppositories, Predictable & Effective Constipation Relief, Bisacodyl 10 mg, 28 Count, 2 pk
Dulcolax

Dulcolax Stimulant Laxative Medicated Suppositories, Predictable & Effective Constipation Relief, Bisacodyl 10 mg, 28 Count, 2 pk

Why we love it
  • Fast relief in minutes.
  • Targets the source directly.
  • Doctor recommended brand.
Main Highlights
  • Includes: Two (2) 28-count boxes of Dulcolax medicated stimulant laxative suppositories
  • Works fast: Dulcolax suppositories provide fast relief from constipation in as little as 15 to 60 minutes
  • Targets the source: Suppositories deliver the active ingredient directly into the rectum for localized relief where it's needed
  • Effective active ingredient: Dulcolax medicated laxative suppositories are made with 10 mg bisacodyl, which stimulates your gut muscles to move things out
  • On-the-go relief: Pack these compact laxative suppositories in your travel essentials to help you get back to being regular when stress and overindulgence slow you down
  • Doctor recommended: Dulcolax is the No. 1 doctor-recommended brand among OTC stimulant laxative brands
  • Comfort-shaped: These laxative suppositories are made to comfortably insert and retain to give you the relief you need
9.7
Exceptional
Amazon Logo
🛡️Trusted by 100M+ UsersWhy?
Best Value
2
9.6
Superb
Fleet Glycerin Suppositories for Constipation Relief, Fast and Effective Stimulant-Free Laxative with Aloe Vera, 100 Count Jar, Pack of 4
Fleet

Fleet Glycerin Suppositories for Constipation Relief, Fast and Effective Stimulant-Free Laxative with Aloe Vera, 100 Count Jar, Pack of 4

Why we love it
  • Fast relief in 15 minutes.
  • Gentle and easy insertion.
  • Doctor-recommended for effectiveness.
Main Highlights
  • Fleet Laxative Glycerin Suppositories provide fast, effective relief from occasional constipation and irregularity in 15 minutes to 1 hour
  • Laxative glycerin suppository works with your body to help gently unblock your system by attracting water into the colon
  • Fleet suppositories' easy to use, lubricated gentle glide tips are uniquely cone-shaped and formulated with soothing aloe for easier insertion
  • Fleet Laxative Glycerin Suppositories are stimulant-free laxatives for constipation relief
  • Fleet is the number one doctor-recommended brand of enemas* and suppositories** *ProVoice Data 2/1/22 to 1/31/23; **IQVIA Survey, 5/1/23 to 4/30/24 and TABS, L52W thru 5/19/24
  • Contains 4 jars of Fleet Laxatives, Laxative Glycerin Suppositories for Adult Constipation, 100 suppositories each
9.6
Superb
Amazon Logo
3
9.6
Superb
Save 37%
Dulcolax Stimulant Laxative Medicated Suppositories, Predictable & Effective Constipation Relief, Bisacodyl 10 mg, 28 Count, Stimulant Laxatives
Dulcolax

Dulcolax Stimulant Laxative Medicated Suppositories, Predictable & Effective Constipation Relief, Bisacodyl 10 mg, 28 Count, Stimulant Laxatives

37% Off
Why we love it
  • Fast relief in 15 minutes.
  • Targets relief where needed.
  • Doctor recommended for effectiveness.
Main Highlights
  • Includes: One (1) 28-count box of Dulcolax medicated stimulant laxative suppositories
  • Works fast: Dulcolax suppositories provide fast relief from constipation in as little as 15 to 60 minutes
  • Targets the source: Suppositories deliver the active ingredient directly into the rectum for localized relief where it's needed
  • Effective active ingredient: Dulcolax medicated laxative suppositories are made with 10 mg bisacodyl, which stimulates your gut muscles to move things out
  • On-the-go relief: Pack these compact laxative suppositories in your travel essentials to help you get back to being regular when stress and overindulgence slow you down
  • Doctor recommended: Dulcolax is the No. 1 doctor-recommended brand among OTC stimulant laxative brands
  • Comfort-shaped: These laxative suppositories are made to comfortably insert and retain to give you the relief you need
9.6
Superb
Save 37%
Amazon Logo
4
9.6
Superb
Pedia-Lax Liquid Glycerin Suppositories for Kids Ages 2-5, Gentle Constipation Relief Laxative for Children, 6 Count, Pack of 3
Pedia-Lax

Pedia-Lax Liquid Glycerin Suppositories for Kids Ages 2-5, Gentle Constipation Relief Laxative for Children, 6 Count, Pack of 3

Why we love it
  • Gentle relief for kids' constipation.
  • Fast-acting within 15-60 minutes.
  • Pediatrician-recommended for safety.
Main Highlights
  • Pedia-Lax Laxative Liquid Glycerin Suppositories provide gentle constipation relief for kids in 15-60 minutes
  • Liquid glycerin suppositories are designed for kids ages 2-5 who experience occasional constipation
  • Small, kid-sized suppositories for constipation are sodium-free and won’t upset the digestive system
  • Pedia-Lax is the number 1 pediatrician-recommended children's laxative brand* *IQVIA, using the ProVoice Survey December 1, 2021 to November 30, 2022)
  • Contains 1 jar of Pedia-Lax Laxative Glycerin Suppositories, 12 count; FSA- and HSA-eligible product in the U.S.
9.6
Superb
Amazon Logo
5
9.5
Superb
Save 14%
The Magic Bullet Suppositories - 4/Sleeves of 5 (Total of 20)
CONCEPTS IN CONFIDENCE

The Magic Bullet Suppositories - 4/Sleeves of 5 (Total of 20)

14% Off
Why we love it
  • Effective and gentle relief.
  • Convenient packaging for on-the-go.
  • Trusted quality from a reputable manufacturer.
Main Highlights
  • The Magic Bullet Suppositories
  • Item Model Number: CCMB100-SL
  • Contains Bisacodyl 10mg in a polyethylene glycol (water soluable) base.
  • Item is sold by 4/Sleeves of 5 (Total of 20)
  • Manufacturer: Concepts In Confidence
9.5
Superb
Save 14%
Amazon Logo
6
9.3
Superb
Save 18%
Fleet Glycerin Suppositories for Constipation Relief, Fast and Effective Stimulant-Free Laxative with Aloe Vera, 50 Count Jar, Pack of 3
Fleet

Fleet Glycerin Suppositories for Constipation Relief, Fast and Effective Stimulant-Free Laxative with Aloe Vera, 50 Count Jar, Pack of 3

18% Off
Why we love it
  • Fast relief within an hour.
  • Gentle and stimulant-free formula.
  • Easy insertion with lubricated tips.
Main Highlights
  • Fleet Laxative Glycerin Suppositories provide fast, effective relief from occasional constipation and irregularity in 15 minutes to 1 hour
  • Laxative glycerin suppository works with your body to help gently unblock your system by attracting water into the colon
  • Fleet suppositories' easy to use, lubricated gentle glide tips are uniquely cone-shaped and formulated with soothing aloe for easier insertion
  • Fleet Laxative Glycerin Suppositories are stimulant-free laxatives for constipation relief
  • Fleet is the number one doctor-recommended brand of enemas* and suppositories** *ProVoice Data 2/1/22 to 1/31/23; **IQVIA Survey, 5/1/23 to 4/30/24 and TABS, L52W thru 5/19/24
9.3
Superb
Save 18%
Amazon Logo
7
9.1
Superb
Fleet Liquid Glycerin Suppositories for Constipation Relief, Fast and Effective Stimulant-Free Laxative, 4 Bottles per Pack, 7.5 mL Each, Pack of 3
Fleet

Fleet Liquid Glycerin Suppositories for Constipation Relief, Fast and Effective Stimulant-Free Laxative, 4 Bottles per Pack, 7.5 mL Each, Pack of 3

Why we love it
  • Fast relief within an hour.
  • Gentle on your system.
  • Doctor-recommended trusted brand.
Main Highlights
  • Fleet Liquid Glycerin Suppositories provide fast, effective relief from occasional constipation and irregularity in 15 minutes to 1 hour
  • Liquid Glycerin Suppository may provide relief from GLP-1 related constipation, consult your doctor
  • Easy-to-use liquid suppositories come with a mess-free suppository applicator and lubricated gentle glide tip for gentle constipation relief
  • Fleet Liquid Glycerin Suppositories are stimulant-free laxatives for constipation relief
  • Fleet is the number one doctor-recommended brand of enemas* and suppositories** *ProVoice Data 2/1/22 to 1/31/23; **IQVIA Survey, 5/1/23 to 4/30/24 and TABS, L52W thru 5/19/24
9.1
Superb
Amazon Logo
8
9.0
Superb
Save 11%
Fleet - Glycerin Suppositories, Laxative, Adult Jar, 100 Each (2-Pack)
Fleet

Fleet - Glycerin Suppositories, Laxative, Adult Jar, 100 Each (2-Pack)

11% Off
Why we love it
  • Gentle relief in minutes.
  • Doctor recommended for effectiveness.
  • Now includes soothing Aloe.
Main Highlights
  • Works in minutes for gentle, effective relief of occasional constipation
  • Doctor Recommended Laxative
  • Now formulated with Aloe
  • Fleet Adult Glycerin Suppository promotes a bowel movement within 15 Minutes to 1 Hour.
  • #1 Doctor-recommended
9.0
Superb
Save 11%
Amazon Logo
9
8.9
Excellent
Save 9%
Fleet Adult Glycerin Suppositories 50-Count (2-Pack)
Fleet Glycerin

Fleet Adult Glycerin Suppositories 50-Count (2-Pack)

9% Off
Why we love it
  • Fast relief within an hour.
  • Convenient alternative to liquid enemas.
  • Aloe formula soothes and comforts.
Main Highlights
  • Each container comes with 50-Adult Suppositories. 2-Pack (100 Suppositories Total)
  • Fleet Adult Glycerin Suppositories promotes a bowel movement within 15 Minutes to 1 Hour.
  • Formulated with Aloe. A convenient alternative for those who prefer not to use liquid enemas.
  • Doctor-recommended glycerin works by attracting water into the stool to promote a bowel movement.
  • Before using Fleet Glycerin Suppositories, be sure to review the complete labeling.
8.9
Excellent
Save 9%
Amazon Logo
10
8.9
Excellent
AVEDANA USP 2g Glycerin Laxatives Suppository – 100 Adult Size Laxative Suppositories for Men and Women – Fast and Gentle Relief Suppositories for Constipation – Comfortable Shape Adult Suppository
AVEDANA

AVEDANA USP 2g Glycerin Laxatives Suppository – 100 Adult Size Laxative Suppositories for Men and Women – Fast and Gentle Relief Suppositories for Constipation – Comfortable Shape Adult Suppository

Why we love it
  • Fast relief from discomfort.
  • Gentle and safe solution.
  • Ergonomic design for easy use.
Main Highlights
  • The Ideal Choice: Say goodbye to pain and discomfort with the Avedana constipation relief suppositories! Our special formula can bring fast and gentle relief that will restore your inner balance and make you feel better again.
  • Fast and Effective: These laxative suppositories can help relieve discomfort within minutes from insertion. Our suppositories may help alleviate constipation symptoms and stimulate bowel movement in 15 minutes to one hour.
  • Gentle Relief: The Avedana glycerin suppositories are an efficient and safe solution to relieve occasional constipation. They have a powerful laxative effect that delivers gentle and fast relief and a soothing effect. Customer Rated No. 1 for Colon
  • Ergonomic Shape: We designed these suppositories for constipation with your health and safety in mind. That is why the Avedana suppositories, compared with other similar products on the market, have a unique shape for easy, painless insertion.
  • How It Works: Our suppository laxative pack is formulated with special ingredients and 2g of glycerin per capsule for maximum benefits. Glycerin absorbs water and can help stimulate bowel movement, so make sure to drink plenty of water for efficient results.
8.9
Excellent
Amazon Logo

Related Deals You Might Like for Suppository For Constipation

📊We scanned 1164 products
🔍
We reviewed the most relevant Suppository For Constipation offers across Amazon and leading retailers, covering major brands and models. Our shortlist features trusted names like Dulcolax, Fleet, Pedia-Lax, CONCEPTS IN CONFIDENCE, Fleet Glycerin, AVEDANA, known for dependable quality and smart design.
⭐
To determine today's best Suppository For Constipation, we analyzed 5821 real customer and expert reviews, focusing on satisfaction, real-world performance and long-term reliability. We also weigh each review's relevance, authenticity and freshness for a fair comparison.

Here's what we found:

🏆 #1
Dulcolax Stimulant Laxative Medicated Suppositories, Predictable & Effective Constipation Relief, Bisacodyl 10 mg, 28 Count, 2 pk

Our overall winner is Dulcolax Stimulant Laxative Medicated Suppositories, Predictable & Effective Constipation Relief, Bisacodyl 10 mg, 28 Count, 2 pk by Dulcolax. It stands out for the right balance of quality, performance and value.

✨ What sets it apart:
✓Fast relief in minutes
✓Targets the source directly
✓Doctor recommended brand
💎 Best Value
Fleet Glycerin Suppositories for Constipation Relief, Fast and Effective Stimulant-Free Laxative with Aloe Vera, 100 Count Jar, Pack of 4

The best value for most shoppers is Fleet Glycerin Suppositories for Constipation Relief, Fast and Effective Stimulant-Free Laxative with Aloe Vera, 100 Count Jar, Pack of 4 by Fleet, with consistently high satisfaction across expert and customer reviews.

💰 Best Deal
Dulcolax Stimulant Laxative Medicated Suppositories, Predictable & Effective Constipation Relief, Bisacodyl 10 mg, 28 Count, Stimulant Laxatives

The strongest deal right now for Suppository For Constipation is Dulcolax Stimulant Laxative Medicated Suppositories, Predictable & Effective Constipation Relief, Bisacodyl 10 mg, 28 Count, Stimulant Laxatives at Dulcolax, currently at 37% off.

🔄Our Suppository For Constipation ranking is updated regularly to reflect new releases and price changes—check back for the latest picks and deals.