10 Best Mouthwash For Mouth Sores of 2026

Last updated on 04/03/2026
Advertising disclosure
Best Choice
1
9.8
Exceptional
Save 20%
ioRinse MR: The Most Dentist & Oncologist-Recommended Oral Ulcer Rinse of its Kind. Maximum Relief of Oral Mucositis, Mouth Sores, Dry Mouth, Canker Sores, Mouth Irritation & Cancer patients, Mint 1 L
Iotech International

ioRinse MR: The Most Dentist & Oncologist-Recommended Oral Ulcer Rinse of its Kind. Maximum Relief of Oral Mucositis, Mouth Sores, Dry Mouth, Canker Sores, Mouth Irritation & Cancer patients, Mint 1 L

20% Off
Why we love it
  • Professional strength trusted by experts.
  • Fast relief you can count on.
  • Gentle on sensitive teeth.
Main Highlights
  • Professional Grade. ioRinse MR has been specially formulated to be effective for both cancer patients undergoing chemotherapy and/or radiation therapy and also non-cancer patients who need professional strength relief. ioRinse MR’s dentist-trusted and oncologist-trusted formula is so unique, it is patented.
  • Perfect for Dry Mouth (Xerostomia) ioRinse MR (Maximum Relief) was created to provide instant and long lasting relief for dry mouth. When you first begin to swish, you will experience a level of soothing lubrication unmatched by other mouthwashes.
  • ioRinse MR is a patented, extra-strength mouthwash that joins the award-winning family of ioRinse products that have won several professional awards and are used in thousands of dental offices where professional strength is needed. Now you can get the same professional strength mouthwash that has earned the trust of both dentists and oncologists, alike.
  • Patient-approved. Many patients have contacted Iotech International to let us know that ioRinse MR has provided them with more relief than any other product that they have tried. No need to suffer further when relief is just a bottle of ioRinse MR away.
  • Alcohol-Free and Gentle on Sensitive Teeth. ioRinse MR is formulated without alcohol, making it ideal for individuals with sensitive teeth or those who prefer an alcohol-free option. It's powerful formula is the choice of leading dentists for its effectiveness.
  • Convenient and Easy to Use. ioRinse MR comes in a 1-liter bottle and is read- to-use, making it perfect for at-home, at-work or on-the-go soothing relief and protection.
  • Fast Relief. ioRinse MR starts working as soon as you start swishing and keeps on working to bring you maximum relief. Its the rinse that health care professionals recommend for safe, rapid-acting relief you can count on.
  • About ioTech: ioTech’s award-winning products are chosen by thousands of dental professionals because of their superior effectiveness. Doctors know the power of ioTech products. Now, these superior products are available direct-to-you. ioTech products are developed and produced here in the USA.
9.8
Exceptional
Save 20%
Amazon Logo
🛡️Trusted by 100M+ UsersWhy?
Best Value
2
9.7
Exceptional
CloSYS Hydrogen Peroxide Mouthwash, 16 oz, Canker Sore Mouthwash, Alcohol-Free, Non-Burning, Cleanses and Heals Mouth Sore Rinse
CloSYS

CloSYS Hydrogen Peroxide Mouthwash, 16 oz, Canker Sore Mouthwash, Alcohol-Free, Non-Burning, Cleanses and Heals Mouth Sore Rinse

Why we love it
  • Cleanses and heals effectively.
  • Multipurpose for various conditions.
  • Gentle, non-burning formula.
Main Highlights
  • CLEANSES AND PROMOTES HEALING: CloSYS Mouth Sores rinse, ideal for people with canker sores, helps cleanse and promote healing of oral sores, mouth burns, and irritation — all while providing a soothing, pleasant oral care routine
  • MULTIPURPOSE USE: CloSYS antiseptic mouthwash is a mouth sores treatment for inflamed gums, canker sores, cheek bites, and irritation from dentures or braces
  • UNIQUE FORMULA: CloSYS mouth sore mouthwash, a CloSYS mouth rinse for mouth sores, has an oxygenating action that helps remove debris, cleaning oral sores to support the normal healing process
  • NON-BURNING, NON-IRRITATING: CloSYS mouth sores treatment for inside mouth does not contain alcohol, sulfates, triclosan, and other ingredients that can burn or irritate the mouth so you can rinse longer to get great results
  • GENTLEST ORAL CARE: CloSYS is the Gentlest Oral Care Ever; CloSYS mouthwash gentle mint flavor freshens breath without burning or stinging - a perfect addition to your bathroom routine
9.7
Exceptional
Amazon Logo
3
9.6
Superb
Save 30%
Colgate Peroxyl Antiseptic Mouth Sore Rinse, Alcohol Free, 1.5% Hydrogen Peroxide, Mild Mint, 8.45 Ounce (Pack of 6)
Colgate

Colgate Peroxyl Antiseptic Mouth Sore Rinse, Alcohol Free, 1.5% Hydrogen Peroxide, Mild Mint, 8.45 Ounce (Pack of 6)

30% Off
Why we love it
  • Promotes healing of oral wounds.
  • Soothes gum inflammation effectively.
  • Alcohol-free for gentle care.
Main Highlights
  • Mouth rinse cleanses and promotes healing of minor oral wounds
  • Antiseptic rinse helps promote healing of: oral sores, irritations, mouth burns
  • Oxygenating action removes oral debris to facilitate healing
  • Soothes minor gum inflammation from dental procedures, dentures and orthodontic appliances
  • 1.5% hydrogen peroxide, alcohol free formula
9.6
Superb
Save 30%
Amazon Logo
4
9.4
Superb
Save 29%
Orajel Nonseptic Mouth Sore Rinse 16oz, Soothing Mint Flavor, Provides Pain Relief, Promotes Healing, 3-Pack
Orajel

Orajel Nonseptic Mouth Sore Rinse 16oz, Soothing Mint Flavor, Provides Pain Relief, Promotes Healing, 3-Pack

29% Off
Why we love it
  • Temporary pain relief guaranteed.
  • Promotes faster healing effectively.
  • Comfortable solution for all sores.
Main Highlights
  • PAIN RELIEF: Orajel Mouthwash helps to provide you with temporary pain relief from your mouth sores and irritation.
  • PROMOTES HEALING: Specially formulated to help kill bacillus in your mouth and promote healing so you can feel better.
  • FOR ALL MOUTH SORES: From canker sores, to cheek bites, gum irritation, and sores from dentures or braces- Orajel Mouth Sore Rinse can help alleviate your pain from the comfort of your home.
  • MINT FLAVOR mouthwash, 16oz
  • #1 Oral Pain Reliever Brand for Adults
9.4
Superb
Save 29%
Amazon Logo
5
9.2
Superb
Oral-B Mouth Sore Mouthwash Special Care Oral Rinse, Hydrogen Peroxide Mouthwash, 16 fl oz, Alcohol Free (Pack of 2)
Oral-B

Oral-B Mouth Sore Mouthwash Special Care Oral Rinse, Hydrogen Peroxide Mouthwash, 16 fl oz, Alcohol Free (Pack of 2)

Why we love it
  • Gentle on sensitive mouths.
  • Effective for various oral irritations.
  • Trusted by dentists and consumers.
Main Highlights
  • The information below is per-pack only
  • 1. UNIQUE ORAL CARE: Oral-B special care rinse is crafted to meet your unique oral care needs, including hydrogen peroxide mouthwash.
  • 2. DENTIST FORMULATED: Specially formulated for Mouth Sores, including: Canker Sores, Cheek Bites, Braces & Denture Irritations, Oral & Gum Irritations
  • 3. CLEANSING ACTION: Cleanses oral wounds.
  • 4. TRUSTED INGREDIENTS: No added alcohol, artificial dyes, parabens, gluten, sodium lauryl Sulfate (SLS). This mouthwash is also alcohol free mouthwash.
  • 5. TRUSTED BRAND: The brand trusted by dentists AND consumers worldwide now brings you the Oral-B special care rinse collection.
9.2
Superb
Amazon Logo
6
9.0
Superb
Oral-B Mouth Sore Mouthwash Special Care Oral Rinse, Hydrogen Peroxide Mouthwash, 16 fl oz, Mouthwash Alcohol Free
Oral-B

Oral-B Mouth Sore Mouthwash Special Care Oral Rinse, Hydrogen Peroxide Mouthwash, 16 fl oz, Mouthwash Alcohol Free

Why we love it
  • Unique solution for oral health.
  • Gentle on mouth sores.
  • Alcohol-free and trusted ingredients.
Main Highlights
  • 1. UNIQUE ORAL CARE: Oral-B special care rinse is crafted to meet your unique oral care needs, including hydrogen peroxide mouthwash.
  • 2. DENTIST FORMULATED: Specially formulated for Mouth Sores, including: Canker Sores, Cheek Bites, Braces & Denture Irritations, Oral & Gum Irritations
  • 3. CLEANSING ACTION: Cleanses oral wounds.
  • 4. TRUSTED INGREDIENTS: No added alcohol, artificial dyes, parabens, gluten, sodium lauryl Sulfate (SLS). This mouthwash is also alcohol free mouthwash.
  • 5. TRUSTED BRAND: The brand trusted by dentists AND consumers worldwide now brings you the Oral-B special care rinse collection.
9.0
Superb
Amazon Logo
7
8.8
Excellent
Save 9%
Prevention Mouth Sore Mouth Rinse, Canker Sore Treatment, Oral Pain Relief Mouthwash for Ulcers and Sores, Braces, with Hydrogen Peroxide, Alcohol-Free, Fluoride Free, 16 oz, Soothing Mint, 1 Pack
PHS Brands

Prevention Mouth Sore Mouth Rinse, Canker Sore Treatment, Oral Pain Relief Mouthwash for Ulcers and Sores, Braces, with Hydrogen Peroxide, Alcohol-Free, Fluoride Free, 16 oz, Soothing Mint, 1 Pack

9% Off
Why we love it
  • Effective relief for mouth sores.
  • Gentle, alcohol-free formula protects.
  • Long-lasting freshness and comfort.
Main Highlights
  • Effective Mouth Sore Treatment: Specially designed for canker sores, ulcers, and irritation caused by braces, burns or minor injuries, this mouth rinse provides fast, soothing relief while supporting healing and oral comfort. Ideal for managing sensitive oral tissue and protecting against further irritation.
  • Alcohol-Free & Gentle Formula: Formulated with hydrogen peroxide, sodium citrate, zinc, and glycerin that work together to provide effective pain relief and protect irritated areas in the mouth, lips, and throat. Made without alcohol, fluoride, or dyes, making it safe for short term daily use and sensitive oral care.
  • Long-Lasting Freshness: Infused with natural menthol and peppermint oil, this refreshing healing mouthwash offers 12 hours of fresh breath while relieving discomfort from mouth sores, ulcers, gum disease and other oral issues.
  • Safe and Easy to Use: This canker sore mouthwash is safe for adults and children aged 2 and older. With early and consistent use, it helps prevent oral discomfort while supporting a healthy, balanced oral environment. For best results, rinse 3-5 times daily or as needed to relieve pain, promote healing, and protect against future irritations.
  • Hydrating & Restorative Care: Rehydrates and moisturizes the oral cavity, ensuring a comfortable experience while serving as an effective mouth sore treatment. Helps to prevent canker sores inside the mouth, dry mouth, and general irritation.
8.8
Excellent
Save 9%
Amazon Logo
8
8.7
Excellent
Canker-X Rincinol Oral Rinse Mouthwash, Quick Pain Relief from Canker Sores, Mouth Burns & More, Benzocaine Free & Alcohol Free Mouthwash, Adults & Kids 6+ Years, 4.0 Fl. Oz.
Canker-X

Canker-X Rincinol Oral Rinse Mouthwash, Quick Pain Relief from Canker Sores, Mouth Burns & More, Benzocaine Free & Alcohol Free Mouthwash, Adults & Kids 6+ Years, 4.0 Fl. Oz.

Why we love it
  • Fast pain relief without burning.
  • Soothes various types of sores.
  • Safe for children and adults.
Main Highlights
  • FAST PAIN RELIEF & HEALING MOUTHWASH: Canker-X canker sore treatment mouthwash provides fast, long-lasting pain relief without any burning or numbing sensation. Canker-X mouthwash is a clinically tested benzocaine-free and alcohol-free formula
  • MOUTH SORES TREATMENT: Canker-X soothes canker sores, cheek bites, mouth burns, gum sores, abrasions from braces and dentures, and other types of mouth sores, relieving pain and promoting healing, while blocking irritants like food and drinks
  • SOOTHES, HYDRATES & PROTECTS: With the goodness of Aloe Vera, Sodium Hyaluronate and Polyvinylpyrrolidone (PVP), this oral care mouthwash works by forming a micro-thin protective coating over mouth sores to quickly relieve pain for up to 6 hours
  • HOW TO USE: Measure 10ml of this canker sore mouthwash using the enclosed cap, and swish it around your mouth for 1 minute. Avoid eating or drinking for at least 1 hour. The Canker-X mouthwash has a pleasant taste and is ideal for multiple mouth sores
  • SAFE & EFFECTIVE: Clinically tested, Canker-X Rincinol Oral Mouthwash is an effective canker sore treatment for both children (6+ years) and adults even if swallowed. Use as needed
8.7
Excellent
Amazon Logo
9
8.7
Excellent
Save 22%
TheraBreath Fresh Breath Mouthwash, Icy Mint Flavor, Alcohol-Free, 16 Fl Oz (Pack of 2)
TheraBreath

TheraBreath Fresh Breath Mouthwash, Icy Mint Flavor, Alcohol-Free, 16 Fl Oz (Pack of 2)

22% Off
Why we love it
  • Fights bad breath effectively.
  • Dentist formulated for trust.
  • ADA accepted, safe and effective.
Main Highlights
  • Two pack 16 fl oz of TheraBreath Fresh Breath Oral Rinse in a Invigorating Icy Mint flavor is a breath freshener mouthwash that’s dentist formulated and alcohol free
  • TheraBreath Fresh Breath is a pH-balanced, non-burning mouthwash that starts working instantly to kill odor-causing bacteria and fight bad breath for 12 hours
  • Every swish of its Invigorating Icy Mint flavor fights bad breath and is certified vegan, gluten free, halal, and kosher; and it comes in recyclable plastic packaging
  • This alcohol-free mouthwash freshens your breath without the burn; it’s made with xylitol, and contains no dyes, no colors, no SLS/sulfates, and no parabens; and is not tested on animals
  • TheraBreath Fresh Breath is made with xylitol to help reduce plaque buildup; this oral rinse is dentist formulated and accepted by the American Dental Association (ADA)
  • For best results, adults should rinse and gargle with 2 teaspoons (10 mL) twice daily for 90 seconds after brushing; children 12-17 should rinse and gargle with 2 teaspoons (10 mL) once daily after brushing
  • Created by Dr. Harold Katz in 1993 for his own family; add TheraBreath mouthwashes to your daily oral care routine and swish with confidence
8.7
Excellent
Save 22%
Amazon Logo
10
8.7
Excellent
Prevention Oncology Alcohol Free Mouthwash, Soothing, Gentle, & Moisturizing, Mouthsore and Dry Mouth Mouthwash Specially Formulated for Patients Undergoing Oncology Treatment - 1-Pack
PHS Brands

Prevention Oncology Alcohol Free Mouthwash, Soothing, Gentle, & Moisturizing, Mouthsore and Dry Mouth Mouthwash Specially Formulated for Patients Undergoing Oncology Treatment - 1-Pack

Why we love it
  • Gentle formulation for sensitive mouths.
  • Alcohol-free for safer use.
  • Soothes discomfort during treatments.
Main Highlights
  • Oncology Specific Formulation - Prevention’s’ over-the-counter (OTC) oncology mouth sore mouthwash has been formulated for use by patients going through chemotherapy and radiation treatment. These treatments can result in uncomfortable mouth sores, ulcers, dry mouth, and other oral complications. This gentle alcohol free mouthwash helps soothe, alleviate and control these side effects, while helping to retain moisture and protect the mucosal lining. The perfect mouth sores treatment for temporary relief of minor discomfort and irritated areas in a sore mouth and sore throat.
  • Soothes & Protects - Unlike standard gum mouthwash products that contain alcohol and other additives, our mouthwash is designed to work with your mouth’s natural functions to support overall oral and gum care. Our mouthwash has no artificial colors or SLS, is alcohol-free and fluoride-free, making it a safe and gentle rinse for oral health support while undergoing treatment.
  • Formulated for Sensitive Mouths - Oncology treatments can lead to oral taste sensitivity and irritation of mouth and throat, so our Oncology mouthwash rinse was created with the goal of minimizing irritants found in other rinses. Our highly effective oral rinse mouthwash features a low-concentration hydrogen peroxide to oxygenate under the gum line to support and maintain gum health, and glycerin to soothe and protect the oral cavity. It acts as a medicated mouthwash to provide temporary pain relief for irritated areas in the mouth, lips and throat, while rehydrating and moisturizing to alleviate dry mouth symptoms.
  • Safe & Easy To Use - This alcohol free mouth wash is safe for all ages over 2 years old and easy to use. Early and regular use of this oral mouthwash will aid in protecting against dry mouth and uncomfortable oral complications. Our rinse is a convenient alternative or supplement for magic mouthwash and may be used in conjunction with other Oncology treatments. We recommend rinsing 3-5 times a day when undergoing chemotherapy and/or radiation treatments.
  • Prevention Health Sciences - Good oral health begins with Prevention! Our complete line of dental rinse and mouthwashes are free of harsh chemicals and ingredients, always naturally flavored, alcohol-free and without any SLS or artificial colors. Our line of oral care products are recommended by health care professionals for both Oncology related oral issues as well as everyday oral care and protection.
8.7
Excellent
Amazon Logo